The track, The 313, sees the British producer team up with singer/songwriter Alana Maria, who is best known for her contribution to house classic Burning by MK.
The title of the track borrows its name from the 313 telephone area code synonymous with the Motor City.
The release of The 313 follows on from two previous singles, Jack Said What (which shares its name with Mac’s label), and One Day, which features vocals from house legend Robert Owens.
Mac has been a figurehead in the house scene since its origins, and has released tracks on labels such as Nervous, Ministry of Sound, Cr2, Toolroom, Saved, Underwater and Ovum, as well as undertaking remixes for the likes of Jamiroquai, Simply Red and Michael Jackson over his 25-year career.
His forthcoming album, Bless This Acid House, features contributions from Marshall Jefferson, Irvine Welsh, E Raze, the late Sleezy D and Robert Owens.
You can download/stream The 313 here.